An interesting case of spongio-fibrosis masking as Peyronie’s
A very nice gentlemen in his 50′s presented with a history of gradual erectile impairment and was now on pharmacologic injection, shots to the penis with medications usually containing prostaglandin E-1 to produce erection.
On erection his penis was not bent, but there was a small crease in the distal shaft. The size of his penis was about 3 times volumetrically of average. He had injected that area on occasion but could not correlate loss of contour with any particular injection.
Thoughts and advice… Injections into the penis have to be compressed just like ideally a vena-puncture in an arm vein for 5 minutes or so. The leakage of blood outside the vascular system is a great stimulus for fibrosis and of course loss of spongy tissue. In this case, spongy tissue of the corpora cavernosa. Injection techniques were reviewed with the patient.
While I do not believe medications for Peyronie’s will help, perhaps in the future stem cell research may be able to replace lost corporal tissue or impaired corporal tissue. Some urologists believe
men with large penises may experience erectile impairment earlier because there is a larger demand for rapid filling.
Harold M. Reed, M.D.