Effect of Circumcision on Female Genitalia
(courtesy of Joshua, unashamedly procirc)
Am J Obstet Gynecol. 2008 Oct 29.
The effects of male circumcision on female partners’ genital tract
symptoms and vaginal
infections in a randomized trial in Rakai, Uganda.
Gray RH, Kigozi G, Serwadda D, Makumbi F, Nalugoda F, Watya S,
Moulton L, Chen MZ,
Sewankambo NK, Kiwanuka N, Sempijja V, Lutalo T, Kagayii J, Wabwire-
Mangen F, Ridzon
R, Bacon M, Wawer MJ.
Departments of Population, Family, and Reproductive Health, Bloomberg
School of Public
Health, Johns Hopkins University, Baltimore, MD.
OBJECTIVE: The objective of the study was to assess effects of male
circumcision on female
genital symptoms and vaginal infections.
STUDY DESIGN: Human immunodeficiency virus (HIV)-negative men
enrolled in a trial
were randomized to immediate or delayed circumcision (control arm).
Genital symptoms,
bacterial vaginosis (BV), and trichomonas were assessed in HIV-
negative wives of married
participants. Adjusted prevalence risk ratios (adjPRR) and 95%
confidence intervals (CIs)
were assessed by multivariable log-binomial regression, intent-to-
treat analyses.
RESULTS: A total of 783 wives of control and 825 wives of
intervention arm men were
comparable at enrollment. BV at enrollment was higher in control
(38.3%) than
intervention arm spouses (30.5%, P = .001). At 1 year follow-up,
intervention arm wives
reported lower rates of genital ulceration (adjPRR, 0.78; 95% CI,
0.63-0.97), but there
were no differences in vaginal discharge or dysuria. The risk of
trichomonas was reduced
in intervention arm wives (adjPRR, 0.52; 95% CI, 0.05-0.98), as were
the risks of any BV
(adjPRR, 0.60; 95% CI, 0.38-0.94) and severe BV (prevalence risk
ratios, 0.39; 95% CI,
0.24-0.64).
CONCLUSION: Male circumcision reduces the risk of ulceration,
trichomonas, and BV in
female partners.
March 24th, 2010 at 10:51 pm
I don’t know about that. I’m not sure I agree with your ideas. I’ll just agree to disagree. Thanks for the post.